Non-erosive gastroesophageal reflux disease (GERD) is a chronic condition where stomach acid frequently flows back into the esophagus, causing heartburn, regurgitation, and chest discomfort—without visible damage to the esophageal lining. Risk factors include obesity, diet, smoking, and certain medications.

Clinical trials offer patients access to emerging therapies and support research into new approaches aimed at reducing acid reflux, improving symptom control, and promoting long-term digestive health.