Lipoprotein(a), or Lp(a), is a type of cholesterol particle in the blood that increases the risk of heart attack and stroke. Unlike regular cholesterol, Lp(a) levels are largely determined by genetics, and lifestyle changes like diet or exercise have little impact. Many people with high Lp(a) are unaware of their condition until cardiovascular issues arise.

Standard cholesterol-lowering medications are often ineffective for reducing Lp(a). Clinical trials offer access to experimental therapies specifically targeting Lp(a) and allow participants to contribute to research aimed at developing new strategies for preventing heart disease.