Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Learn about MASLD and emerging approaches to liver health.

MASLD is a liver condition caused by the buildup of fat due to metabolic disorders, not alcohol use. Some people experience fatigue and upper abdominal discomfort, while others remain symptom-free until routine medical tests reveal the condition. Globally, MASLD affects millions and can cause serious liver damage if left untreated.

Those at higher risk often have obesity, type 2 diabetes, high cholesterol, or insulin resistance. Clinical trials are exploring new medications and lifestyle interventions to reduce liver fat, slow disease progression, and help patients maintain long-term liver health.